8D4U
Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Neutrophil elastase | polymer | 218 | 23319.0 | 2 | UniProt (P08246) Pfam (PF00089) In PDB | Homo sapiens (human) | Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase |
| 2 | C, D | Extracellular Adherence Protein | polymer | 100 | 11023.4 | 2 | UniProt (Q99QS1) Pfam (PF03642) In PDB | Staphylococcus aureus subsp. aureus | Protein map |
| 3 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
C, D: 158 - 254 (UniProt: Q99QS1)
| PDB | External Database | Details |
|---|---|---|
| Gly 155 | - | expression tag |
| Ser 156 | - | expression tag |
| Thr 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68684.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 70047.1 |
