8D0R
Human FUT9 bound to GDP and H-Type 2
Summary for 8D0R
Entry DOI | 10.2210/pdb8d0r/pdb |
Related | 8D0O 8D0P 8D0Q |
Descriptor | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | glycosyltransferase, alpha-(1, 3)-fucosyltransferase, gt 10, gt-b fold, inverting mechanism, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 39886.26 |
Authors | Kadirvelraj, R.,Wood, Z.A. (deposition date: 2022-05-26, release date: 2023-05-24, Last modification date: 2023-10-25) |
Primary citation | Kadirvelraj, R.,Boruah, B.M.,Wang, S.,Chapla, D.,Huang, C.,Ramiah, A.,Hudson, K.L.,Prudden, A.R.,Boons, G.J.,Withers, S.G.,Wood, Z.A.,Moremen, K.W. Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19:1022-1030, 2023 Cited by PubMed: 37202521DOI: 10.1038/s41589-023-01345-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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