8CWU

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing nanobody 1-21

Summary for 8CWU

• Entry DOI: 10.2210/pdb8cwu/pdb
• Descriptor: Spike protein S1, VHH 1-21, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: cross-neutralizing antibody; nanobody; sars-cov-2; sarbecovirus; immune system; vhh, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2,2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 40045.65

Authors

Liu, H.,Wilson, I.A. (deposition date: 2022-05-19, release date: 2022-07-06, Last modification date: 2023-10-18)

• Primary citation: Xiang, Y.,Huang, W.,Liu, H.,Sang, Z.,Nambulli, S.,Tubiana, J.,Williams Jr., K.L.,Duprex, W.P.,Schneidman-Duhovny, D.,Wilson, I.A.,Taylor, D.J.,Shi, Y.; Superimmunity by pan-sarbecovirus nanobodies.; Cell Rep, 39:111004-111004, 2022; PubMed: 35738279; DOI: 10.1016/j.celrep.2022.111004

Experimental method

X-RAY DIFFRACTION (1.71 Å)