8C1A

SARS-CoV-2 NSP3 macrodomain in complex with aztreonam

Summary for 8C1A

Entry DOI	10.2210/pdb8c1a/pdb
Descriptor	Replicase polyprotein 1ab, aztreonam, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	macrodomain, adp-ribose, sars-cov-2, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	2
Total formula weight	36855.03
Authors	Schuller, M.,Ahel, I. (deposition date: 2022-12-20, release date: 2023-03-08, Last modification date: 2024-02-07)
Primary citation	Schuller, M.,Zarganes-Tzitzikas, T.,Bennett, J.,De Cesco, S.,Fearon, D.,von Delft, F.,Fedorov, O.,Brennan, P.E.,Ahel, I. Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors. Pathogens, 12:-, 2023 Cited by PubMed: 36839595 DOI: 10.3390/pathogens12020324 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation