8C17
Crystal structure of TEAD4 in complex with peptide 1
Summary for 8C17
Entry DOI | 10.2210/pdb8c17/pdb |
Descriptor | Transcriptional enhancer factor TEF-3, Stapled peptide, GLYCEROL, ... (5 entities in total) |
Functional Keywords | complex, inhibitor, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 28260.91 |
Authors | Scheufler, C.,Kallen, J. (deposition date: 2022-12-20, release date: 2023-03-15, Last modification date: 2024-05-29) |
Primary citation | Mesrouze, Y.,Gubler, H.,Villard, F.,Boesch, R.,Ottl, J.,Kallen, J.,Reid, P.C.,Scheufler, C.,Marzinzik, A.L.,Chene, P. Biochemical and Structural Characterization of a Peptidic Inhibitor of the YAP:TEAD Interaction That Binds to the alpha-Helix Pocket on TEAD. Acs Chem.Biol., 18:643-651, 2023 Cited by PubMed: 36825662DOI: 10.1021/acschembio.2c00936 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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