8BRO

Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-fucosylamide

Summary for 8BRO

Entry DOI	10.2210/pdb8bro/pdb
Descriptor	Lectin, 5-[3-(aminomethyl)phenyl]-~{N}-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]furan-2-carboxamide (3 entities in total)
Functional Keywords	lectin, fucosylamides, antiadhesive drug, sugar binding protein
Biological source	Burkholderia cenocepacia
Total number of polymer chains	1
Total formula weight	14373.31
Authors	Varrot, A.,Lunstrom, J. (deposition date: 2022-11-23, release date: 2023-02-08, Last modification date: 2024-06-19)
Primary citation	Mazzotta, S.,Antonini, G.,Vasile, F.,Gillon, E.,Lundstrom, J.,Varrot, A.,Belvisi, L.,Bernardi, A. Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from Burkholderia cenocepacia. Molecules, 28:-, 2023 Cited by PubMed: 36771163 DOI: 10.3390/molecules28031494 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation