8BJL
Human Aldose Reductase in Complex with a Ligand with a Fluoro-Indol-Acetic-Acid Structure (Schl44172)
Summary for 8BJL
Entry DOI | 10.2210/pdb8bjl/pdb |
Descriptor | aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-(6-fluoranylindol-1-yl)ethanoic acid, ... (7 entities in total) |
Functional Keywords | human aldose reductase, har, aldo-keto-reductase, schl44172 ligand, nadp+, diabetes, closed pocket, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37404.47 |
Authors | |
Primary citation | Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S.,Schlitzer, M. Human Aldose Reductase in Complex with a Ligand with a Fluoro-Indol-Acetic-Acid Structure (Schl44172) To Be Published, |
Experimental method | X-RAY DIFFRACTION (0.97 Å) |
Structure validation
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