8BJL

Human Aldose Reductase in Complex with a Ligand with a Fluoro-Indol-Acetic-Acid Structure (Schl44172)

Summary for 8BJL

• Entry DOI: 10.2210/pdb8bjl/pdb
• Descriptor: aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-(6-fluoranylindol-1-yl)ethanoic acid, ... (7 entities in total)
• Functional Keywords: human aldose reductase, har, aldo-keto-reductase, schl44172 ligand, nadp+, diabetes, closed pocket, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37404.47

Authors

Hubert, L.-S.,Heine, A.,Klebe, G. (deposition date: 2022-11-04, release date: 2023-11-15, Last modification date: 2026-03-04)

• Primary citation: Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S.,Schlitzer, M.; Human Aldose Reductase in Complex with a Ligand with a Fluoro-Indol-Acetic-Acid Structure (Schl44172); To Be Published,

Experimental method

X-RAY DIFFRACTION (0.97 Å)