8ADZ
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2
Summary for 8ADZ
Entry DOI | 10.2210/pdb8adz/pdb |
EMDB information | 15376 |
Descriptor | IgM Fab, light chain, IgM Fab, heavy chain, IgM C2-domain from mouse, ... (7 entities in total) |
Functional Keywords | full-length human immunoglobulin m, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 17 |
Total formula weight | 559150.73 |
Authors | Chen, Q.,Rosenthal, P.,Tolar, P. (deposition date: 2022-07-12, release date: 2022-10-26, Last modification date: 2022-11-09) |
Primary citation | Chen, Q.,Menon, R.,Calder, L.J.,Tolar, P.,Rosenthal, P.B. Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer. Nat Commun, 13:6314-6314, 2022 Cited by PubMed: 36274064DOI: 10.1038/s41467-022-34090-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.7 Å) |
Structure validation
Download full validation report