8ADZ

Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L, V	IgM Fab, light chain	polymer	215	23367.9	2		Homo sapiens (human)
2	H, U	IgM Fab, heavy chain	polymer	226	24574.7	2		Homo sapiens (human)
3	I, B	IgM C2-domain from mouse	polymer	117	12769.6	2		Homo sapiens (human)
4	M, N, O, Q, E...	Immunoglobulin heavy constant mu	polymer	383	41875.8	10	Pfam (PF07654) UniProt (by SIFTS) (P01871) In PDB	Homo sapiens (human)
5	J	Immunoglobulin J chain	polymer	136	15483.3	1	Pfam (PF15097) UniProt (by SIFTS) (P01591) In PDB	Homo sapiens (human)
6	A, T, C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
7	G, R, K, S, M...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	17
	Total formula weight	555665.4
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	10
	Total formula weight	2212.1
All*	Total formula weight	559150.7

*Water molecules are not included.