8ADF
X-ray crystal structure of PPAR gamma ligand binding domain in complex with CZ39
Summary for 8ADF
Entry DOI | 10.2210/pdb8adf/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, (2R)-3-(4-bromophenyl)-2-(3-hydroxyphenyl)-4-oxidanyl-2H-furan-5-one (3 entities in total) |
Functional Keywords | nuclear receptor, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 69533.79 |
Authors | Capelli, D.,Montanari, R.,Pochetti, G.,Meneghetti, F.,Villa, S. (deposition date: 2022-07-08, release date: 2023-04-26, Last modification date: 2024-02-07) |
Primary citation | Capelli, D.,Cazzaniga, G.,Mori, M.,Laghezza, A.,Loiodice, F.,Quaglia, M.,Negro, E.,Meneghetti, F.,Villa, S.,Montanari, R. Biological Screening and Crystallographic Studies of Hydroxy gamma-Lactone Derivatives to Investigate PPAR gamma Phosphorylation Inhibition. Biomolecules, 13:-, 2023 Cited by PubMed: 37189440DOI: 10.3390/biom13040694 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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