7ZYS

Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2227

Summary for 7ZYS

• Entry DOI: 10.2210/pdb7zys/pdb
• Descriptor: Serine protease subunit NS2B, Serine protease NS3, 1-[(8~{R},15~{S},18~{S})-18-(4-azanylbutyl)-15-butyl-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(26),22,24-trien-8-yl]guanidine, ... (4 entities in total)
• Functional Keywords: flavivirin, serine protease, viral protein, ns2b-ns3, zika virus
• Biological source: Zika virus; More
• Total number of polymer chains: 2
• Total formula weight: 25518.74

Authors

Huber, S.,Steinmetzer, T. (deposition date: 2022-05-25, release date: 2022-07-13, Last modification date: 2024-01-31)

• Primary citation: Huber, S.,Braun, N.,Steinmetzer, T.; Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2227; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.26 Å)