7ZYO
Compound 9 Bound to CK2alpha
Summary for 7ZYO
Entry DOI | 10.2210/pdb7zyo/pdb |
Descriptor | Casein kinase II subunit alpha, ADENOSINE-5'-TRIPHOSPHATE, ACETATE ION, ... (5 entities in total) |
Functional Keywords | fragment based drug discovery, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40281.77 |
Authors | Brear, P.,Hyvonen, M. (deposition date: 2022-05-25, release date: 2022-10-12, Last modification date: 2024-01-31) |
Primary citation | Brear, P.,De Fusco, C.,Atkinson, E.L.,Iegre, J.,Francis-Newton, N.J.,Venkitaraman, A.R.,Hyvonen, M.,Spring, D.R. A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action. Rsc Med Chem, 13:1420-1426, 2022 Cited by PubMed: 36426237DOI: 10.1039/d2md00161f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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