7ZW5

Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2259

Summary for 7ZW5

• Entry DOI: 10.2210/pdb7zw5/pdb
• Descriptor: Serine protease subunit NS2B, Serine protease NS3, 1-[(8R,15S,18S)-15-(4-azanylbutyl)-18-(2-carbamimidamidoethyl)-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(25),22(26),23-trien-8-yl]guanidine, ... (4 entities in total)
• Functional Keywords: flavivirin, serine protease, viral protein, ns2b-ns3, zika virus
• Biological source: Zika virus; More
• Total number of polymer chains: 2
• Total formula weight: 25547.75

Authors

Huber, S.,Steinmetzer, T. (deposition date: 2022-05-18, release date: 2023-05-31, Last modification date: 2024-02-07)

• Primary citation: Huber, S.,Braun, N.,Steinmetzer, T.; Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2259; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.38 Å)