7ZUM
Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2130
Summary for 7ZUM
Entry DOI | 10.2210/pdb7zum/pdb |
Descriptor | Serine protease subunit NS2B, Serine protease NS3, 1-[(5R,8R,15S,18S)-15-(4-azanylbutyl)-5-(cyclohexylmethyl)-18-(1H-indol-3-ylmethyl)-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(25),22(26),23-trien-8-yl]guanidine, ... (4 entities in total) |
Functional Keywords | flavivirin, serine protease, viral protein, ns2b-ns3, zika virus |
Biological source | Zika virus More |
Total number of polymer chains | 2 |
Total formula weight | 25687.97 |
Authors | Huber, S.,Steinmetzer, T. (deposition date: 2022-05-12, release date: 2023-03-22, Last modification date: 2024-02-07) |
Primary citation | Huber, S.,Braun, N.,Steinmetzer, T. Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2130 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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