7ZRQ

1.68 Angstrom crystal structure of Ca/CaM-E140G:CaMKIIdelta peptide complex

Summary for 7ZRQ

• Entry DOI: 10.2210/pdb7zrq/pdb
• Descriptor: Calmodulin-1, Calcium/calmodulin-dependent protein kinase type II subunit delta, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: calcium-binding protein, calmodulin, cam, camkii, kinase, metal binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 19416.70

Authors

Helassa, N.,Antonyuk, S. (deposition date: 2022-05-04, release date: 2022-12-28, Last modification date: 2024-01-31)

• Primary citation: Prakash, O.,Gupta, N.,Milburn, A.,McCormick, L.,Deugi, V.,Fisch, P.,Wyles, J.,Thomas, N.L.,Antonyuk, S.,Dart, C.,Helassa, N.; Calmodulin variant E140G associated with long QT syndrome impairs CaMKII delta autophosphorylation and L-type calcium channel inactivation.; J.Biol.Chem., 299:102777-102777, 2022; PubMed: 36496072; DOI: 10.1016/j.jbc.2022.102777

Experimental method

X-RAY DIFFRACTION (1.68 Å)