7ZN5
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry.
Summary for 7ZN5
Entry DOI | 10.2210/pdb7zn5/pdb |
Related | 7PQ9 7ZLA |
EMDB information | 14801 |
Descriptor | PLP-dependent aminotransferase family protein, DNA (48-MER) (3 entities in total) |
Functional Keywords | transcription factor, plp-binding protein, domain-swap homodimer, dna binding protein |
Biological source | Alkalihalobacillus clausii More |
Total number of polymer chains | 4 |
Total formula weight | 140560.30 |
Authors | Freda, I.,Montemiglio, L.C.,Tramonti, A.,Contestabile, R.,Vallone, B.,Exertier, C.,Savino, C.,Chaves Sanjuan, A.,Bolognesi, M. (deposition date: 2022-04-20, release date: 2023-07-05, Last modification date: 2024-01-17) |
Primary citation | Freda, I.,Exertier, C.,Barile, A.,Chaves-Sanjuan, A.,Vega, M.V.,Isupov, M.N.,Harmer, N.J.,Gugole, E.,Swuec, P.,Bolognesi, M.,Scipioni, A.,Savino, C.,Di Salvo, M.L.,Contestabile, R.,Vallone, B.,Tramonti, A.,Montemiglio, L.C. Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51:8237-8254, 2023 Cited by PubMed: 37378428DOI: 10.1093/nar/gkad552 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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