7ZLE
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP
Summary for 7ZLE
Entry DOI | 10.2210/pdb7zle/pdb |
Related | 6FSN 7ZHB 7ZKC |
Descriptor | UDP-glucose-glycoprotein glucosyltransferase-like protein, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | glycoprotein, misfolding, transferase, endoplasmic reticulum. udp, gt24 |
Biological source | Chaetomium thermophilum |
Total number of polymer chains | 1 |
Total formula weight | 36429.15 |
Authors | Roversi, P.,Zitzmann, N.,Bayo, Y.,Le Cornu, J.D. (deposition date: 2022-04-14, release date: 2022-06-22, Last modification date: 2024-10-16) |
Primary citation | Caputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Roversi, P.,Zitzmann, N. A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.823 Å) |
Structure validation
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