7ZL5

Azosemide in complex with Carbonic Anhydrase I

This is a non-PDB format compatible entry.

Summary for 7ZL5

• Entry DOI: 10.2210/pdb7zl5/pdb
• Descriptor: Carbonic anhydrase 1, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: carbonic anhydrase, inhibitor, metalloenzyme, azosemide, loop diuretic, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 58763.00

Authors

Angeli, A.,Ferraroni, M. (deposition date: 2022-04-14, release date: 2023-04-26, Last modification date: 2024-02-07)

• Primary citation: Ferraroni, M.,Angeli, A.,Pinteala, M.,Supuran, C.T.; Sulfonamide diuretic azosemide as an efficient carbonic anhydrase inhibitor; J.Mol.Struct., 1268:133672-, 2022; DOI: 10.1016/j.molstruc.2022.133672

Experimental method

X-RAY DIFFRACTION (1.479 Å)