7ZK7

ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC

Summary for 7ZK7

• Entry DOI: 10.2210/pdb7zk7/pdb
• EMDB information: 14757
• Descriptor: ATP-dependent translocase ABCB1, (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ... (4 entities in total)
• Functional Keywords: abc transporter, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 1
• Total formula weight: 148224.73

Authors

Parey, K.,Januliene, D.,Gewering, T.,Moeller, A. (deposition date: 2022-04-12, release date: 2023-04-26)

• Primary citation: Gewering, T.,Waghray, D.,Parey, K.,Januliene, D.,Urbatsch, I.,Moeller, A.,Zhang, Q.; ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)