7ZJT

Crystal structure of HsaD from Mycobacterium tuberculosis at 1.96 A resolution

Summary for 7ZJT

Entry DOI	10.2210/pdb7zjt/pdb
Descriptor	4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	hsad, m. tuberculosis, cholesterol, hydrolase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	2
Total formula weight	66203.68
Authors	Barelier, S.,Roig-Zamboni, V.,Cavalier, J.F.,Sulzenbacher, G. (deposition date: 2022-04-11, release date: 2022-09-28, Last modification date: 2024-02-07)
Primary citation	Barelier, S.,Avellan, R.,Gnawali, G.R.,Fourquet, P.,Roig-Zamboni, V.,Poncin, I.,Point, V.,Bourne, Y.,Audebert, S.,Camoin, L.,Spilling, C.D.,Canaan, S.,Cavalier, J.F.,Sulzenbacher, G. Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis. Febs J., 290:1563-1582, 2023 Cited by PubMed: 36197115 DOI: 10.1111/febs.16645 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation