7ZHB

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2)

Summary for 7ZHB

• Entry DOI: 10.2210/pdb7zhb/pdb
• Related: 6FSN
• Descriptor: UDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (7 entities in total)
• Functional Keywords: glycoprotein, misfolding, transferase, endoplasmic reticulum. udp-glucose, gt24
• Biological source: Chaetomium thermophilum
• Total number of polymer chains: 1
• Total formula weight: 36926.72

Authors

Roversi, P.,Zitzmann, N.,Bayo, Y.,Le Cornu, J.D. (deposition date: 2022-04-06, release date: 2022-04-20, Last modification date: 2024-10-09)

• Primary citation: Caputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Roversi, P.,Zitzmann, N.; A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.89 Å)