7ZHB

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 2)

7ZHB の概要

• エントリーDOI: 10.2210/pdb7zhb/pdb
• 関連するPDBエントリー: 6FSN
• 分子名称: UDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (7 entities in total)
• 機能のキーワード: glycoprotein, misfolding, transferase, endoplasmic reticulum. udp-glucose, gt24
• 由来する生物種: Chaetomium thermophilum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36926.72

構造登録者

Roversi, P.,Zitzmann, N.,Bayo, Y.,Le Cornu, J.D. (登録日: 2022-04-06, 公開日: 2022-04-20, 最終更新日: 2024-10-09)

• 主引用文献: Caputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Roversi, P.,Zitzmann, N.; A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint; To Be Published,

実験手法

X-RAY DIFFRACTION (1.89 Å)