7ZGJ
Trypanosoma brucei gambiense ISG65 in complex with human complement component C3
Summary for 7ZGJ
Entry DOI | 10.2210/pdb7zgj/pdb |
EMDB information | 14707 |
Descriptor | Complement C3 beta chain, Complement C3, 65 kDa invariant surface glycoprotein, putative (3 entities in total) |
Functional Keywords | complement, complex, immune system |
Biological source | Trypanosoma brucei gambiense More |
Total number of polymer chains | 3 |
Total formula weight | 225386.71 |
Authors | Suelzen, H.,Zoll, S. (deposition date: 2022-04-03, release date: 2023-04-05, Last modification date: 2024-03-27) |
Primary citation | Sulzen, H.,Began, J.,Dhillon, A.,Kereiche, S.,Pompach, P.,Votrubova, J.,Zahedifard, F.,Subrtova, A.,Safner, M.,Hubalek, M.,Thompson, M.,Zoltner, M.,Zoll, S. Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. Nat Commun, 14:2403-2403, 2023 Cited by PubMed: 37105991DOI: 10.1038/s41467-023-37988-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.58 Å) |
Structure validation
Download full validation report