7ZGA

Structure of yeast Sec14p with ergoline

Summary for 7ZGA

Entry DOI	10.2210/pdb7zga/pdb
Descriptor	SEC14 cytosolic factor, ~{O}9-methyl ~{O}4-[2,2,2-tris(chloranyl)ethyl] (5~{a}~{S},6~{a}~{S},9~{R},10~{a}~{S})-7-methyl-3-nitro-5,5~{a},6,6~{a},8,9,10,10~{a}-octahydroindolo[4,3-fg]quinoline-4,9-dicarboxylate (3 entities in total)
Functional Keywords	sec14p, ergoline, lipid binding protein
Biological source	Saccharomyces cerevisiae S288C
Total number of polymer chains	1
Total formula weight	34524.33
Authors	Hong, Z.,Johnen, P.,Schaaf, G.,Bono, F. (deposition date: 2022-04-03, release date: 2023-01-25, Last modification date: 2024-02-07)
Primary citation	Chen, X.R.,Poudel, L.,Hong, Z.,Johnen, P.,Katti, S.,Tripathi, A.,Nile, A.H.,Green, S.M.,Khan, D.,Schaaf, G.,Bono, F.,Bankaitis, V.A.,Igumenova, T.I. Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity. J.Biol.Chem., 299:102861-102861, 2023 Cited by PubMed: 36603766 DOI: 10.1016/j.jbc.2022.102861 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.302 Å)

Structure validation