7ZFX
VDR complex with Aromatic-D-Ring Analog
Summary for 7ZFX
Entry DOI | 10.2210/pdb7zfx/pdb |
Descriptor | Vitamin D3 receptor A, Nuclear receptor coactivator 1, ACETATE ION, ... (5 entities in total) |
Functional Keywords | complex, agonist, vitamin d receptor, transcription |
Biological source | Danio rerio (zebrafish) More |
Total number of polymer chains | 2 |
Total formula weight | 36394.53 |
Authors | Rochel, N. (deposition date: 2022-04-01, release date: 2022-11-23, Last modification date: 2024-01-31) |
Primary citation | Seoane, S.,Gogoi, P.,Zarate-Ruiz, A.,Peluso-Iltis, C.,Peters, S.,Guiberteau, T.,Maestro, M.A.,Perez-Fernandez, R.,Rochel, N.,Mourino, A. Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1 alpha ,25-Dihydroxyvitamin D 3. J.Med.Chem., 65:13112-13124, 2022 Cited by PubMed: 36166643DOI: 10.1021/acs.jmedchem.2c00900 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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