7ZB9

Crystal structure of CYP124 in complex with inhibitor carbethoxyhexyl imidazole in the absence of glycerol (NoCryo)

Summary for 7ZB9

Entry DOI	10.2210/pdb7zb9/pdb
Descriptor	CYP124 in complex with inhibitor carbethoxyhexyl imidazole, PROTOPORPHYRIN IX CONTAINING FE, ethyl 7-imidazol-1-ylheptanoate, ... (7 entities in total)
Functional Keywords	carbethoxyhexyl imidazole, cyp124, mtb, tuberculosis, inhibitor, glycerol, oxidoreductase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	1
Total formula weight	50099.58
Authors	Bukhdruker, S.,Varaksa, T.,Marin, E.,Gilep, A.,Strushkevich, N.,Borshchevskiy, V. (deposition date: 2022-03-23, release date: 2023-01-11, Last modification date: 2024-03-27)
Primary citation	Bukhdruker, S.,Varaksa, T.,Orekhov, P.,Grabovec, I.,Marin, E.,Kapranov, I.,Kovalev, K.,Astashkin, R.,Kaluzhskiy, L.,Ivanov, A.,Mishin, A.,Rogachev, A.,Gordeliy, V.,Gilep, A.,Strushkevich, N.,Borshchevskiy, V. Structural insights into the effects of glycerol on ligand binding to cytochrome P450. Acta Crystallogr D Struct Biol, 79:66-77, 2023 Cited by PubMed: 36601808 DOI: 10.1107/S2059798322011019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.15 Å)

Structure validation