7Z9R
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 2Up1Down conformation
Summary for 7Z9R
Entry DOI | 10.2210/pdb7z9r/pdb |
Related | 7Z6V 7Z7X 7Z85 7Z86 7Z9Q |
EMDB information | 14576 |
Descriptor | Spike glycoprotein,Fibritin, Nanobody H11-H4 Q98R H100E, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | complex, spike glycoprotein, nanobody h11-h4 q98r h100e, antiviral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 6 |
Total formula weight | 476196.32 |
Authors | Weckener, M.,Naismith, J.H. (deposition date: 2022-03-21, release date: 2022-07-13, Last modification date: 2022-10-05) |
Primary citation | Mikolajek, H.,Weckener, M.,Brotzakis, Z.F.,Huo, J.,Dalietou, E.V.,Le Bas, A.,Sormanni, P.,Harrison, P.J.,Ward, P.N.,Truong, S.,Moynie, L.,Clare, D.K.,Dumoux, M.,Dormon, J.,Norman, C.,Hussain, N.,Vogirala, V.,Owens, R.J.,Vendruscolo, M.,Naismith, J.H. Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes. Proc.Natl.Acad.Sci.USA, 119:e2205412119-e2205412119, 2022 Cited by PubMed: 35858383DOI: 10.1073/pnas.2205412119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
Download full validation report