7Z9P

The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic

7Z9P の概要

• エントリーDOI: 10.2210/pdb7z9p/pdb
• 分子名称: DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: clostridiodes difficile, antibiotic, dna-binding, drug discovery, target identification, dna
• 由来する生物種: synthetic construct (32630)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 23845.16

構造登録者

Mason, S.,Leonard, P.M. (登録日: 2022-03-21, 公開日: 2023-03-29, 最終更新日: 2024-02-07)

• 主引用文献: Mason, C.S.,Avis, T.,Hu, C.,Nagalingam, N.,Mudaliar, M.,Coward, C.,Begum, K.,Gajewski, K.,Alam, M.J.,Basseres, E.,Moss, S.,Reich, S.,Duperchy, E.,Fox, K.R.,Garey, K.W.,Powell, D.J.; The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic.; Antimicrob.Agents Chemother., 67:e0156322-e0156322, 2023; PubMed: 37093023; DOI: 10.1128/aac.01563-22

実験手法