7Z8U

Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP

Summary for 7Z8U

Entry DOI	10.2210/pdb7z8u/pdb
Descriptor	ATP phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	atp, phosphoribosyltransferase, atpprt, prpp, hisg, hisgz, histidine, biosynthesis, allosteric, transferase
Biological source	Psychrobacter arcticus
Total number of polymer chains	1
Total formula weight	26076.41
Authors	Alphey, M.S.,Fisher, G.,da Silva, R.G. (deposition date: 2022-03-18, release date: 2022-03-30, Last modification date: 2024-02-07)
Primary citation	Fisher, G.,Corbella, M.,Alphey, M.S.,Nicholson, J.,Read, B.J.,Kamerlin, S.C.L.,da Silva, R.G. Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation. Nat Commun, 13:7607-7607, 2022 Cited by PubMed: 36494361 DOI: 10.1038/s41467-022-34960-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation