7Z6Z
Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with fosinoprilat
Summary for 7Z6Z
Entry DOI | 10.2210/pdb7z6z/pdb |
Descriptor | Angiotensin-converting enzyme, soluble form, ACETATE ION, 1,2-ETHANEDIOL, ... (17 entities in total) |
Functional Keywords | angiotensin-1 converting enzyme, fosinoprilat, fosinopril, metalloprotease, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 151909.36 |
Authors | Cozier, G.E.,Acharya, K.R. (deposition date: 2022-03-14, release date: 2022-06-22, Last modification date: 2024-01-31) |
Primary citation | Cozier, G.E.,Newby, E.C.,Schwager, S.L.U.,Isaac, R.E.,Sturrock, E.D.,Acharya, K.R. Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat. Febs J., 289:6659-6671, 2022 Cited by PubMed: 35653492DOI: 10.1111/febs.16543 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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