7Z5A

Crystal structure of the trapped complex of mouse Endonuclease VIII-LIKE 3 (mNEIL3) and hairpin DNA with 5'overhang

Summary for 7Z5A

• Entry DOI: 10.2210/pdb7z5a/pdb
• Descriptor: Endonuclease 8-like 3, DNA (5'-D(P*TP*TP*TP*(PED)P*AP*CP*GP*CP*GP*AP*AP*GP*CP*GP*TP*G)-3'), ZINC ION, ... (4 entities in total)
• Functional Keywords: ap-icl, dna crosslink repair, neil3, ber, dna binding protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 39364.81

Authors

Silhan, J.,Huskova, A. (deposition date: 2022-03-08, release date: 2022-10-19, Last modification date: 2024-01-31)

• Primary citation: Huskova, A.,Dinesh, D.C.,Srb, P.,Boura, E.,Veverka, V.,Silhan, J.; Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model.; Nucleic Acids Res., 50:10436-10448, 2022; PubMed: 36155818; DOI: 10.1093/nar/gkac793

Experimental method

X-RAY DIFFRACTION (2.28 Å)