7Z26
Crystal structure of YTHDF2 YTH domain in complex with m6A RNA
Summary for 7Z26
| Entry DOI | 10.2210/pdb7z26/pdb |
| Descriptor | YTH domain-containing family protein 2, RNA (5'-R(P*(6MZ)P*CP*U)-3'), SULFATE ION, ... (5 entities in total) |
| Functional Keywords | epitranscriptomic reader, m6a reader, rna binding protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 42219.99 |
| Authors | Nai, F.,Nachawati, R.,Li, Y.,Caflisch, A. (deposition date: 2022-02-25, release date: 2022-03-16, Last modification date: 2024-02-07) |
| Primary citation | Nai, F.,Nachawati, R.,Zalesak, F.,Wang, X.,Li, Y.,Caflisch, A. Fragment Ligands of the m 6 A-RNA Reader YTHDF2. Acs Med.Chem.Lett., 13:1500-1509, 2022 Cited by PubMed: 36110386DOI: 10.1021/acsmedchemlett.2c00303 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report
