7Z0X
THSC20.HVTR26 Fab bound to SARS-CoV-2 Receptor Binding Domain
Summary for 7Z0X
Entry DOI | 10.2210/pdb7z0x/pdb |
Descriptor | THSC20.HVTR26 Fab heavy chain, THSC20.HVTR26 Fab light chain, Spike protein S1, ... (6 entities in total) |
Functional Keywords | neutralizing antibody, sars-cov-2, spike, rbd, antiviral protein, immunology |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 71557.85 |
Authors | Wibmer, C.K. (deposition date: 2022-02-23, release date: 2022-04-13, Last modification date: 2022-05-11) |
Primary citation | Hingankar, N.,Deshpande, S.,Das, P.,Rizvi, Z.A.,Wibmer, C.K.,Mashilo, P.,Ansari, M.Y.,Burns, A.,Barman, S.,Zhao, F.,Mukherjee, S.,Torres, J.L.,Chattopadhyay, S.,Mehdi, F.,Sutar, J.,Rathore, D.K.,Pargai, K.,Singh, J.,Sonar, S.,Jakhar, K.,Dandotiya, J.,Bhattacharyya, S.,Mani, S.,Samal, S.,Singh, S.,Kshetrapal, P.,Thiruvengadam, R.,Batra, G.,Medigeshi, G.,Ward, A.B.,Bhatnagar, S.,Awasthi, A.,Sok, D.,Bhattacharya, J. A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant. Plos Pathog., 18:e1010465-e1010465, 2022 Cited by PubMed: 35482816DOI: 10.1371/journal.ppat.1010465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report