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7Z0X

THSC20.HVTR26 Fab bound to SARS-CoV-2 Receptor Binding Domain

Summary for 7Z0X
Entry DOI10.2210/pdb7z0x/pdb
DescriptorTHSC20.HVTR26 Fab heavy chain, THSC20.HVTR26 Fab light chain, Spike protein S1, ... (6 entities in total)
Functional Keywordsneutralizing antibody, sars-cov-2, spike, rbd, antiviral protein, immunology
Biological sourceHomo sapiens
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Total number of polymer chains3
Total formula weight71557.85
Authors
Wibmer, C.K. (deposition date: 2022-02-23, release date: 2022-04-13, Last modification date: 2022-05-11)
Primary citationHingankar, N.,Deshpande, S.,Das, P.,Rizvi, Z.A.,Wibmer, C.K.,Mashilo, P.,Ansari, M.Y.,Burns, A.,Barman, S.,Zhao, F.,Mukherjee, S.,Torres, J.L.,Chattopadhyay, S.,Mehdi, F.,Sutar, J.,Rathore, D.K.,Pargai, K.,Singh, J.,Sonar, S.,Jakhar, K.,Dandotiya, J.,Bhattacharyya, S.,Mani, S.,Samal, S.,Singh, S.,Kshetrapal, P.,Thiruvengadam, R.,Batra, G.,Medigeshi, G.,Ward, A.B.,Bhatnagar, S.,Awasthi, A.,Sok, D.,Bhattacharya, J.
A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant.
Plos Pathog., 18:e1010465-e1010465, 2022
Cited by
PubMed: 35482816
DOI: 10.1371/journal.ppat.1010465
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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