7YTV

Crystal structure of Aspergillus fumigatus Thioredoxin reductase in complex with auranofin

Summary for 7YTV

Entry DOI	10.2210/pdb7ytv/pdb
Descriptor	Thioredoxin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	thioredoxin reductase, reductase, auranofin, oxidoreductase
Biological source	Aspergillus fumigatus
Total number of polymer chains	2
Total formula weight	82781.93
Authors	Lin, W. (deposition date: 2022-08-16, release date: 2023-06-28, Last modification date: 2023-11-29)
Primary citation	Chen, P.,Yang, J.,Jin, Y.,Lu, C.,Feng, Z.,Gao, F.,Chen, Y.,Wang, F.,Shang, Z.,Lin, W. In vitro antifungal and antibiofilm activities of auranofin against itraconazole-resistant Aspergillus fumigatus. J Mycol Med, 33:101381-101381, 2023 Cited by PubMed: 37037064 DOI: 10.1016/j.mycmed.2023.101381 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.866 Å)

Structure validation