7YSE

Crystal structure of E. coli heterotetrameric GlyRS in complex with tRNA

7YSE の概要

• エントリーDOI: 10.2210/pdb7yse/pdb
• 分子名称: Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, RNA (76-MER), ... (6 entities in total)
• 機能のキーワード: aminoacyl-trna synthetase, hetertetramer, drug target, protein-trna complex, transferase, transferase-rna complex, transferase/rna
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 275554.86

構造登録者

Han, L.,Ju, Y.,Zhou, H. (登録日: 2022-08-12, 公開日: 2023-02-01, 最終更新日: 2023-11-29)

• 主引用文献: Han, L.,Luo, Z.,Ju, Y.,Chen, B.,Zou, T.,Wang, J.,Xu, J.,Gu, Q.,Yang, X.L.,Schimmel, P.,Zhou, H.; The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.; Sci Adv, 9:eadf1027-eadf1027, 2023; PubMed: 36753552; DOI: 10.1126/sciadv.adf1027

実験手法

X-RAY DIFFRACTION (2.907 Å)