7YRU
ALK2 antibody complex
Summary for 7YRU
Entry DOI | 10.2210/pdb7yru/pdb |
Descriptor | Activin receptor type-1, antibody heavy chain, antibody light chain, ... (4 entities in total) |
Functional Keywords | alk2, protein binding, transferase-immune system complex, immune system, transferase/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 59973.15 |
Authors | Kawaguchi, Y.,Nakamura, K.,Suzuki, M.,Tsuji, S.,Katagiri, T. (deposition date: 2022-08-10, release date: 2023-05-17, Last modification date: 2023-06-07) |
Primary citation | Katagiri, T.,Tsukamoto, S.,Kuratani, M.,Tsuji, S.,Nakamura, K.,Ohte, S.,Kawaguchi, Y.,Takaishi, K. A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. Nat Commun, 14:2960-2960, 2023 Cited by PubMed: 37231012DOI: 10.1038/s41467-023-38746-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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