7YMH
Cryo-EM structure of Nb29-alpha1AAR-miniGsq complex bound to noradrenaline
Summary for 7YMH
Entry DOI | 10.2210/pdb7ymh/pdb |
Related | 7YM8 |
EMDB information | 33924 33928 |
Descriptor | alpha1A-adrenergic receptor, miniGsq, Nb29, ... (4 entities in total) |
Functional Keywords | gpcr, nanobody, agonist, complex, membrane protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 98293.98 |
Authors | Toyoda, Y.,Zhu, A.,Yan, C.,Kobilka, B.K.,Liu, X. (deposition date: 2022-07-28, release date: 2023-07-05) |
Primary citation | Toyoda, Y.,Zhu, A.,Kong, F.,Shan, S.,Zhao, J.,Wang, N.,Sun, X.,Zhang, L.,Yan, C.,Kobilka, B.K.,Liu, X. Structural basis of alpha 1A -adrenergic receptor activation and recognition by an extracellular nanobody. Nat Commun, 14:3655-3655, 2023 Cited by PubMed: 37339967DOI: 10.1038/s41467-023-39310-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.52 Å) |
Structure validation
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