7YK7

Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex

7YK7 の概要

• エントリーDOI: 10.2210/pdb7yk7/pdb
• EMDBエントリー: 33889
• 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(i) subunit alpha-2, Relaxin-3 receptor 2, ... (6 entities in total)
• 機能のキーワード: human relaxin family peptide receptor 4, g protein-coupled receptor, ligand recognition, structural protein
• 由来する生物種: Bos taurus (Bovine); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 154358.86

構造登録者

Chen, Y.,Zhou, Q.T.,Wang, J.,Xu, Y.W.,Wang, Y.,Yan, J.H.,Wang, Y.B.,Zhu, Q.,Zhao, F.H.,Li, C.H.,Chen, C.W.,Cai, X.Q.,Bathgate, R.A.D.,Shen, C.,Xu, H.E.,Yang, D.H.,Liu, H.,Wang, M.W. (登録日: 2022-07-21, 公開日: 2023-03-01)

• 主引用文献: Chen, Y.,Zhou, Q.,Wang, J.,Xu, Y.,Wang, Y.,Yan, J.,Wang, Y.,Zhu, Q.,Zhao, F.,Li, C.,Chen, C.W.,Cai, X.,Bathgate, R.A.D.,Shen, C.,Eric Xu, H.,Yang, D.,Liu, H.,Wang, M.W.; Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4).; Nat Commun, 14:492-492, 2023; PubMed: 36717591; DOI: 10.1038/s41467-023-36182-z

実験手法

ELECTRON MICROSCOPY (2.75 Å)