7YDG
Crystal structure of human SARS2 catalytic domain with a disease related mutation
Summary for 7YDG
Entry DOI | 10.2210/pdb7ydg/pdb |
Related | 7YDF |
Descriptor | Serine--tRNA ligase, mitochondrial (1 entity in total) |
Functional Keywords | mitochondrial seryl-trna synthetase, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 157639.31 |
Authors | Wu, S.,Li, P.,Zhou, X.L.,Fang, P. (deposition date: 2022-07-04, release date: 2022-11-02, Last modification date: 2023-11-29) |
Primary citation | Yu, T.,Zhang, Y.,Zheng, W.Q.,Wu, S.,Li, G.,Zhang, Y.,Li, N.,Yao, R.,Fang, P.,Wang, J.,Zhou, X.L. Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease. Nucleic Acids Res., 50:11755-11774, 2022 Cited by PubMed: 36350636DOI: 10.1093/nar/gkac1028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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