7YB7
anti-apoptotic protein BCL-2-M12
Summary for 7YB7
Entry DOI | 10.2210/pdb7yb7/pdb |
Descriptor | Apoptosis regulator Bcl-2,Bcl-2-like protein 1, cp2 peptide, N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide, ... (4 entities in total) |
Functional Keywords | bcl-2, m12 mutants, anti-apoptotic, cyclic peptide, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 38628.75 |
Authors | |
Primary citation | Li, F.,Liu, J.,Liu, C.,Liu, Z.,Peng, X.,Huang, Y.,Chen, X.,Sun, X.,Wang, S.,Chen, W.,Xiong, D.,Diao, X.,Wang, S.,Zhuang, J.,Wu, C.,Wu, D. Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy. Nat Commun, 15:1476-1476, 2024 Cited by PubMed: 38368459DOI: 10.1038/s41467-024-45848-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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