7Y65
Cryo-EM structure of C5a peptide-bound C5aR1 in complex with Gi protein
Summary for 7Y65
Entry DOI | 10.2210/pdb7y65/pdb |
EMDB information | 33634 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | complex, agonist, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 155470.34 |
Authors | Feng, Y.Y.,Zhao, C.,Yan, W.,Shao, Z.H. (deposition date: 2022-06-18, release date: 2023-03-01, Last modification date: 2023-04-19) |
Primary citation | Feng, Y.,Zhao, C.,Deng, Y.,Wang, H.,Ma, L.,Liu, S.,Tian, X.,Wang, B.,Bin, Y.,Chen, P.,Yan, W.,Fu, P.,Shao, Z. Mechanism of activation and biased signaling in complement receptor C5aR1. Cell Res., 33:312-324, 2023 Cited by PubMed: 36806352DOI: 10.1038/s41422-023-00779-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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