7Y36

Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex

Summary for 7Y36

• Entry DOI: 10.2210/pdb7y36/pdb
• EMDB information: 33588 33590
• Descriptor: Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total)
• Functional Keywords: teriparatide, pth1r, cryo-em structure, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 192995.99

Authors

Zhai, X.,Mao, C.,Shen, Q.,Zang, S.,Shen, D.,Zhang, H.,Chen, Z.,Wang, G.,Zhang, C.,Zhang, Y.,Liu, Z. (deposition date: 2022-06-10, release date: 2023-07-05, Last modification date: 2025-07-02)

• Primary citation: Zhai, X.,Mao, C.,Shen, Q.,Zang, S.,Shen, D.,Zhang, H.,Chen, Z.,Wang, G.,Zhang, C.,Zhang, Y.,Liu, Z.; Cryo-EM structure of the Teriparatide-bound human PTH1R-Gs complex; to be published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)