7Y0I

Solution structures of ASH1L PHD domain in complex with H3K4me2 peptide

7Y0I の概要

• エントリーDOI: 10.2210/pdb7y0i/pdb
• 分子名称: Histone-lysine N-methyltransferase ASH1L, ALA-ARG-THR-MLY-GLN-THR-ALA-ARG-LYS-SER-THR-GLY-GLY-LYS-ALA, ZINC ION (3 entities in total)
• 機能のキーワード: ash1l, phd domain, h3k4me2, prostate cancer, structural protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8170.11

構造登録者

Yu, M.,Zeng, L. (登録日: 2022-06-05, 公開日: 2022-10-12)

• 主引用文献: Yu, M.,Jia, Y.,Ma, Z.,Ji, D.,Wang, C.,Liang, Y.,Zhang, Q.,Yi, H.,Zeng, L.; Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.; Front Oncol, 12:906807-906807, 2022; PubMed: 36033518; DOI: 10.3389/fonc.2022.906807

実験手法

SOLUTION NMR