7Y02
Crystal structure of Ricin A chain bound with (S)-2-(2-amino-4-oxo-3,4-dihydropteridine-7-carboxamido)-3-(4-fluorophenyl)propanoic acid
Summary for 7Y02
Entry DOI | 10.2210/pdb7y02/pdb |
Related | 7XZS 7XZT 7XZU 7XZW |
Descriptor | Ricin A chain, (2S)-2-[(2-azanyl-4-oxidanylidene-3H-pteridin-7-yl)carbonylamino]-3-(4-fluorophenyl)propanoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase inhibitor, hydrolase |
Biological source | Ricinus communis (castor bean) |
Total number of polymer chains | 1 |
Total formula weight | 31833.56 |
Authors | Goto, M.,Higashi, S.,Ohba, T.,Kawata, R.,Nagatsu, K.,Suzuki, S.,Saito, R. (deposition date: 2022-06-03, release date: 2022-12-21, Last modification date: 2023-11-29) |
Primary citation | Goto, M.,Higashi, S.,Ohba, T.,Kawata, R.,Nagatsu, K.,Suzuki, S.,Anslyn, E.V.,Saito, R. Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket. Biochem.Biophys.Res.Commun., 627:1-4, 2022 Cited by PubMed: 35998389DOI: 10.1016/j.bbrc.2022.08.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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