7XW7

TSHR-K1-70 complex

This is a non-PDB format compatible entry.

Summary for 7XW7

• Entry DOI: 10.2210/pdb7xw7/pdb
• EMDB information: 33493
• Descriptor: K1-70 scFv, Thyrotropin receptor (2 entities in total)
• Functional Keywords: thyroid-stimulating hormone, thyroid-stimulating hormone receptor, ths, thsr, gpcr, gs, k1-70, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 104294.92

Authors

Duan, J.,Xu, P.,Luan, X.,Ji, Y.,Yuan, Q.,He, X.,Ye, J.,Cheng, X.,Jiang, H.,Zhang, S.,Jiang, Y.,Xu, H.E. (deposition date: 2022-05-26, release date: 2022-08-17, Last modification date: 2024-03-13)

• Primary citation: Duan, J.,Xu, P.,Luan, X.,Ji, Y.,He, X.,Song, N.,Yuan, Q.,Jin, Y.,Cheng, X.,Jiang, H.,Zheng, J.,Zhang, S.,Jiang, Y.,Xu, H.E.; Hormone- and antibody-mediated activation of the thyrotropin receptor.; Nature, 609:854-859, 2022; PubMed: 35940204; DOI: 10.1038/s41586-022-05173-3

Experimental method

ELECTRON MICROSCOPY (5.5 Å)