7XR6
Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613
Summary for 7XR6
Entry DOI | 10.2210/pdb7xr6/pdb |
EMDB information | 33408 |
Descriptor | Excitatory amino acid transporter 2, (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid, CHOLESTEROL HEMISUCCINATE, ... (5 entities in total) |
Functional Keywords | glutamate transport, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 213950.44 |
Authors | |
Primary citation | Zhang, Z.,Chen, H.,Geng, Z.,Yu, Z.,Li, H.,Dong, Y.,Zhang, H.,Huang, Z.,Jiang, J.,Zhao, Y. Structural basis of ligand binding modes of human EAAT2. Nat Commun, 13:3329-3329, 2022 Cited by PubMed: 35680945DOI: 10.1038/s41467-022-31031-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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