7XO3
Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Summary for 7XO3
Entry DOI | 10.2210/pdb7xo3/pdb |
EMDB information | 33335 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | amyloid fibril, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 86856.65 |
Authors | |
Primary citation | Fan, Y.,Sun, Y.,Yu, W.,Tao, Y.,Xia, W.,Liu, Y.,Zhao, Q.,Tang, Y.,Sun, Y.,Liu, F.,Cao, Q.,Wu, J.,Liu, C.,Wang, J.,Li, D. Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease. Structure, 31:78-, 2023 Cited by PubMed: 36513068DOI: 10.1016/j.str.2022.11.013 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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