7XMS
CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14
Summary for 7XMS
Entry DOI | 10.2210/pdb7xms/pdb |
EMDB information | 33303 |
Descriptor | Somatostatin receptor type 4, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | g protein-coupled receptor, somatostatin receptor 4, cryo-em, structural protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 160866.99 |
Authors | Wenli, Z.,Shuo, H.,Na, Q.,Wenbo, Z.,Mengjie, L.,Dehua, Y.,Ming-Wei, W.,Wu, B.,Zhao, Q. (deposition date: 2022-04-26, release date: 2022-08-03, Last modification date: 2022-08-17) |
Primary citation | Zhao, W.,Han, S.,Qiu, N.,Feng, W.,Lu, M.,Zhang, W.,Wang, M.,Zhou, Q.,Chen, S.,Xu, W.,Du, J.,Chu, X.,Yi, C.,Dai, A.,Hu, L.,Shen, M.Y.,Sun, Y.,Zhang, Q.,Ma, Y.,Zhong, W.,Yang, D.,Wang, M.W.,Wu, B.,Zhao, Q. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32:761-772, 2022 Cited by PubMed: 35739238DOI: 10.1038/s41422-022-00679-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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