7XMF
Cryo-EM structure of human NaV1.7/beta1/beta2-Nav1.7-IN2
Summary for 7XMF
Entry DOI | 10.2210/pdb7xmf/pdb |
EMDB information | 33295 |
Descriptor | Isoform 3 of Sodium channel protein type 9 subunit alpha,Green fluorescent protein, Sodium channel subunit beta-1,Green fluorescent protein, Sodium channel subunit beta-2, ... (6 entities in total) |
Functional Keywords | sodium channel, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 337091.39 |
Authors | Zhang, J.T.,Jiang, D.H. (deposition date: 2022-04-25, release date: 2022-11-30, Last modification date: 2022-12-28) |
Primary citation | Zhang, J.,Shi, Y.,Huang, Z.,Li, Y.,Yang, B.,Gong, J.,Jiang, D. Structural basis for Na V 1.7 inhibition by pore blockers. Nat.Struct.Mol.Biol., 29:1208-1216, 2022 Cited by PubMed: 36424527DOI: 10.1038/s41594-022-00860-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.07 Å) |
Structure validation
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