7XME
Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative
Summary for 7XME
Entry DOI | 10.2210/pdb7xme/pdb |
Descriptor | Polymerase basic protein 2, IODIDE ION, (2~{S},3~{S})-3-[[5-dimethoxyphosphoryl-4-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, rna binding protein |
Biological source | Influenza A virus (A/Victoria/3/1975(H3N2)) |
Total number of polymer chains | 4 |
Total formula weight | 77969.13 |
Authors | Zhang, Z. (deposition date: 2022-04-25, release date: 2023-05-03, Last modification date: 2023-11-29) |
Primary citation | Zhang, Z.,Liu, X. Discovery of a novel azaindole derivatives targeting the influenza PB2 cap binding region To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.521 Å) |
Structure validation
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